Tirzepatide Intermediates

Tirzepatide side chain:
Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH
Cas:2915356-76-0
C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH
Cas:1188328-37-1

Short peptides
Fmoc-Thr(tBu)-Phe-OH
CAS:1962160-86-6
Using this material can reduce the risk of threonine coupling racemic and impurity generation.

FMOC-ILE-AIB-OH
CAS:2171139-20-9
Using this material can be more convenient than FMOC-AIB decoupling

Fmoc-Ser(tBu)-Gly-OH
CAS: 81672-17-5
The use of Fmoc-Ser(tBu)-Gly-OH instead of Fmoc-Ser(tBu)-OH and FMOC-GLY-OH can prevent the formation of Fmoc-ser(OtBu)-Gly-GLY-OH impurities in the synthesis, and the presence of Fmoc-ser(OtBu)-Gly-GLY-OH in the crude product will seriously affect the purification yield.

FMOC-PRO-PRO-OH
CAS: 129223-22-9
This can be used to reduce the synthesis time.

For any enquiries about P29/diapeptides/side chain/semaglutide api/tirzepatide api, plz feel free to contact me.
Tel: +8618575536586
Email: haoran.tse@gmail.com