Star Weight Loss Drug - Comprehensive Analysis Of Oral Semaglutide

A diabetes treatment drug called "Semaglutide" is rapidly gaining popularity due to its excellent weight loss results. Even Tesla CEO Elon Musk is full of praise for it, once revealing that the secret to losing 9 kilograms in a month is to fast and take semaglutide regularly.
Semaglutide Growth Trajectory:
In December 2017, the U.S. Food and Drug Administration (FDA) officially approved semaglutide injection for blood sugar control in adults with type 2 diabetes.
In September 2019, the US FDA approved Rybelsus (oral semaglutide) for medical use.
In January 2020, the FDA granted its new use approval again to reduce the risk of major adverse cardiovascular events in adult patients with type 2 diabetes mellitus with cardiovascular disease. In December of the same year, Novo Nordisk submitted a marketing application to the FDA for semaglutide 2.4mg subcutaneously once a week for weight loss.
In April 2021, the State Food and Drug Administration (NMPA) also approved its use in China for the treatment of type 2 diabetes in adults and to reduce the risk of cardiovascular adverse events in patients with T2DM and cardiovascular disease.
In June 2021, the FDA further approved it for the treatment of obesity, allowing semaglutide (Wegovy) injection to be used in adult obese individuals with a BMI of ≥30 or adults with a BMI of ≥27 with at least one weight-related condition, such as hypertension, type 2 diabetes, or dyslipidemia. Studies have shown that obese patients treated with semaglutide lose an average of 17%-18% of their weight over 68 weeks.
In January 2023, the FDA approved a new indication for Wegovy (semaglutide injection) for chronic weight management in pediatric patients with an age- and sex-adjusted initial body mass index (BMI) of 95% or more, 12 years of age and older, as an adjunct to low-calorie diets and increased physical activity. This is one of the few drugs in the world that is currently officially approved by the FDA for the treatment of obesity.
Oral semaglutide is highly regarded as the high-profile drug of the year. The following is a summary of several questions about semaglutide that everyone is most concerned about for reference.

Is Rybelsus safe and effective?
Semaglutide is a GLP-1 drug that is considered the most promising weight loss ingredient. Among them, Novo Nordisk's oral semaglutide products are currently the most comprehensively rated choice among oral tablets.
Semaglutide has been on the market for more than six years and is widely regarded as one of the safest weight loss drugs in history, with millions of users around the world verifying its effectiveness, with significant weight loss effects, mild side effects, ease of use, stable ingredients, long shelf life, and no need for cold chain storage.
Official clinical data show that overweight people lose an average of 18.1% of their weight after 48 weeks of continuous use of semaglutide, proving its effectiveness. The drug primarily achieves calorie and weight loss goals by reducing food intake.

Can people with a BMI less than 30 use it?
It can be used, but it is not recommended for people who are underweight or hypoglycemic.
For people with moderate weight who only want to lose weight slightly and relieve body anxiety, you can choose a low-dose regimen, which can also achieve good results.

How to plan a medication regimen?
According to official guidelines, the starting dose should be 3mg for everyone. After using this dose continuously for at least one month, consider increasing the dose to 7 mg if it is well tolerated. After another month, the dose can be further increased to 14 mg if appropriate. Users usually begin to lose significant weight from the second or third week after taking 7 mg orally.
Unlike traditional weight loss methods that focus on boosting metabolism or promoting gastrointestinal emptying, long-term use of semaglutide can help reduce visceral fat levels, stabilize blood sugar, and improve unhealthy eating habits.
For people of moderate weight who do not need to lose significant weight, long-term use of 3mg or 7mg doses can help control weight. Consult with a healthcare professional.
Note that semaglutide is indicated for BMI≥30, or BMI≥27 with at least one comorbidity. It is not recommended for people who are underweight or have low blood sugar problems.

What are the adverse reactions after use?
Common adverse reactions include nausea, dizziness, vomiting, gastrointestinal discomfort, dehydration, etc., and most symptoms are mild without excessive use. Discomfort may usually only occur in the first few days of use and gradually decrease as continued use as the body needs time to adjust to GLP-1. At the same time, the results of the study showed that about 2-4% of the population does not absorb the components of the drug at all.
Please read the drug instructions carefully before taking the drug, which lists in detail the contraindications to medication, including people with liver and kidney insufficiency, patients with thyroid disease, people trying to conceive, lactating women, etc.

Is there anything special about your diet that needs attention?
There are no hard and fast requirements, but it is recommended to avoid or reduce foods high in oil and sugar, as well as heavy salt and spicy foods.
The drug mainly helps diet and weight loss by suppressing appetite, and if you overeat after taking the drug, it may affect the effect. At the same time, the body may reject a large amount of greasy food and alcohol at one time, leading to vomiting and other conditions.

If I forget to take my medicine one day, do I need to take a refill?
No, you don't. If you forget to take your medicine one day, skip that day and continue to take the medicine as originally planned the next day.
In addition, it is not recommended to combine two 7mg capsules as 14mg, nor to divide one 14mg capsule into two halves as two 7mg capsules.

How to deal with weight loss plateau?
The weight loss plateau is when the body's self-protection mechanisms are at work. With weight loss, not only fat is lost, but water and muscle are also reduced, leading to lower metabolic levels. The body tends to retain more energy and burn less calories, slowing down weight loss.
There is no need to worry when encountering a stagnant period of weight loss, through some changes, you can break the inertia of weight loss and reach the weight loss goal faster. Here are a few suggestions: · Break the body's inertia: Try to use market-proven effective weight loss drugs (such as semaglutide, etc.) to prolong fasting time and change metabolic patterns. Adjust your diet: Maintain your body's calorie balance and adjust the portion and frequency of meals under the premise of balance. Increase dietary variety: Lack of vitamins and minerals can lead to ineffective use of calories and nutrients. Adequate protein intake can increase metabolic levels and avoid muscle loss. Change exercise habits: Reduced muscle mass can lead to lower basal metabolism and slower weight loss. It can appropriately increase the time and frequency of exercise and accelerate fat burning.

How do I stop taking medication after reaching my target weight?
Normally, users can achieve a weight loss of 10-18% after a period of use.
After reaching the goal, it is recommended to continue using the current dose for one month to help the body adjust to the new weight state and form good eating habits. This can help reduce the magnitude of weight regain after discontinuation.
Users usually gradually return to normal appetite within one to two weeks of stopping the drug, and if they do not control their diet, there may be a certain degree of rebound. Therefore, it is necessary to maintain a healthy diet and lifestyle habits after stopping the drug.